SLPI (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SLPI partial ORF ( NP_003055, 33 a.a. - 132 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (57)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLPI
Entrez GeneID
6590GeneBank Accession#
NM_003064Protein Accession#
NP_003055Gene Name
SLPI
Gene Alias
ALK1, ALP, BLPI, HUSI, HUSI-I, MPI, WAP4, WFDC4
Gene Description
secretory leukocyte peptidase inhibitor
Omim ID
107285Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity. [provided by RefSeq
Other Designations
OTTHUMP00000031775|WAP four-disulfide core domain 4|antileukoproteinase|mucus proteinase inhibitor|secretory leukocyte protease inhibitor (antileukoproteinase)|seminal proteinase inhibitor
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Interactome
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Publication Reference
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Activated microglia enhance neurogenesis via trypsinogen secretion.
Nikolakopoulou AM, Dutta R, Chen Z, Miller RH, Trapp BD.
PNAS 2013 May; 110(21):8714.
Application：Array, MS, Recombinant protein.
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Activated microglia enhance neurogenesis via trypsinogen secretion.
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