SLC22A5 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human SLC22A5 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SLC22A5
Entrez GeneID
6584GeneBank Accession#
BC012325.1Protein Accession#
AAH12325.1Gene Name
SLC22A5
Gene Alias
CDSP, FLJ46769, OCTN2, OCTN2VT
Gene Description
solute carrier family 22 (organic cation/carnitine transporter), member 5
Gene Ontology
HyperlinkGene Summary
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. [provided by RefSeq
Other Designations
high-affinity sodium dependent carnitine cotransporter|organic cation transporter 2|organic cation transporter 5|organic cation/carnitine transporter 2|solute carrier family 22 (organic cation transporter), member 5|solute carrier family 22 member 5
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Interactome
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Disease
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