SLC18A2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SLC18A2 partial ORF ( NP_003045, 53 a.a. - 151 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HEKNATEIQTARPVHTASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (70); Rat (69)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC18A2
Entrez GeneID
6571GeneBank Accession#
NM_003054Protein Accession#
NP_003045Gene Name
SLC18A2
Gene Alias
MGC120477, MGC120478, MGC26538, SVAT, SVMT, VAT2, VMAT2
Gene Description
solute carrier family 18 (vesicular monoamine), member 2
Omim ID
193001Gene Ontology
HyperlinkGene Summary
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM
Other Designations
OTTHUMP00000020576|vesicle monoamine transporter type 2
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Interactome
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Disease
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