SLC12A2 monoclonal antibody (M01), clone 5H7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC12A2.
Immunogen
SLC12A2 (NP_001037.1, 903 a.a. ~ 1010 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVPLNVADQKLLE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.62 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SLC12A2 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — SLC12A2
Entrez GeneID
6558GeneBank Accession#
NM_001046Protein Accession#
NP_001037.1Gene Name
SLC12A2
Gene Alias
BSC, BSC2, MGC104233, NKCC1
Gene Description
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
Omim ID
600840Gene Ontology
HyperlinkGene Summary
By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia (Payne et al., 1995 [PubMed 7629105]). See also SLC12A1 (MIM 600839) and SLC12A3 (MIM 600968).[supplied by OMIM
Other Designations
basolateral Na-K-Cl symporter|bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
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Interactome
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Pathway
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Disease
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