SLC11A1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SLC11A1 full-length
Host
Human
Theoretical MW (kDa)
19.69
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SLC11A1 antibody (H00006556-B01) by Western Blots.
SDS-PAGE Gel
SLC11A1 transfected lysate.
Western Blot
Lane 1: SLC11A1 transfected lysate ( 19.69 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SLC11A1
Entrez GeneID
6556GeneBank Accession#
BC041787.1Protein Accession#
-Gene Name
SLC11A1
Gene Alias
LSH, NRAMP, NRAMP1
Gene Description
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Gene Ontology
HyperlinkGene Summary
This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq
Other Designations
natural resistance-associated macrophage protein 1|solute carrier family 11 (sodium/phosphate symporters), member 1
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Pathway
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Disease
- Abortion
- Alzheimer disease
- Anemia
- Arthritis
- Asthma
- Atherosclerosis
- Autoimmune Diseases
- Behcet Syndrome
- Brucellosis
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