SLC11A1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SLC11A1 full-length ORF ( AAH41787.1, 1 a.a. - 178 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLRNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRYHPSVPQLFRPGREQLLLLPPLTSPSQSLFYPAVPSEAGLLPCFPEM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
45.6
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC11A1
Entrez GeneID
6556GeneBank Accession#
BC041787.1Protein Accession#
AAH41787.1Gene Name
SLC11A1
Gene Alias
LSH, NRAMP, NRAMP1
Gene Description
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Gene Ontology
HyperlinkGene Summary
This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq
Other Designations
natural resistance-associated macrophage protein 1|solute carrier family 11 (sodium/phosphate symporters), member 1
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Pathway
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Disease
- Abortion
- Alzheimer disease
- Anemia
- Arthritis
- Asthma
- Atherosclerosis
- Autoimmune Diseases
- Behcet Syndrome
- Brucellosis
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