SLC11A1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SLC11A1 protein.
Immunogen
SLC11A1 (AAH41787.1, 1 a.a. ~ 178 a.a) full-length human protein.
Sequence
MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLRNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRYHPSVPQLFRPGREQLLLLPPLTSPSQSLFYPAVPSEAGLLPCFPEM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SLC11A1 expression in transfected 293T cell line (H00006556-T01) by SLC11A1 MaxPab polyclonal antibody.
Lane 1: SLC11A1 transfected lysate(19.58 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SLC11A1
Entrez GeneID
6556GeneBank Accession#
BC041787.1Protein Accession#
AAH41787.1Gene Name
SLC11A1
Gene Alias
LSH, NRAMP, NRAMP1
Gene Description
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Gene Ontology
HyperlinkGene Summary
This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq
Other Designations
natural resistance-associated macrophage protein 1|solute carrier family 11 (sodium/phosphate symporters), member 1
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Pathway
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Disease
- Abortion
- Alzheimer disease
- Anemia
- Arthritis
- Asthma
- Atherosclerosis
- Autoimmune Diseases
- Behcet Syndrome
- Brucellosis
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