SLC8A3 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human SLC8A3 full-length ORF ( NP_891981.1, 1 a.a. - 284 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
57.5
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC8A3
Entrez GeneID
6547GeneBank Accession#
NM_182936.1Protein Accession#
NP_891981.1Gene Name
SLC8A3
Gene Alias
NCX3
Gene Description
solute carrier family 8 (sodium/calcium exchanger), member 3
Omim ID
607991Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq
Other Designations
Na(+)/Ca(2+)-exchange protein 3|Na+/Ca2+ exchanger 3|OTTHUMP00000179116|sodium-calcium exchanger form 3|sodium/calcium exchanger SLC8A3|solute carrier family 8 (sodium-calcium exchanger), member 3
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Interactomes
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Pathways
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Diseases
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