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SLC8A3 rabbit monoclonal antibody

  • Catalog # : H00006547-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SLC8A3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SLC8A3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SLC8A3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6547
  • Gene Name:
  • SLC8A3
  • Gene Alias:
  • NCX3
  • Gene Description:
  • solute carrier family 8 (sodium/calcium exchanger), member 3
  • Gene Summary:
  • This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq
  • Other Designations:
  • Na(+)/Ca(2+)-exchange protein 3,Na+/Ca2+ exchanger 3,OTTHUMP00000179116,sodium-calcium exchanger form 3,sodium/calcium exchanger SLC8A3,solute carrier family 8 (sodium-calcium exchanger), member 3
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