SLC8A3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SLC8A3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SLC8A3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SLC8A3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SLC8A3
Entrez GeneID
6547GeneBank Accession#
SLC8A3Gene Name
SLC8A3
Gene Alias
NCX3
Gene Description
solute carrier family 8 (sodium/calcium exchanger), member 3
Omim ID
607991Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq
Other Designations
Na(+)/Ca(2+)-exchange protein 3|Na+/Ca2+ exchanger 3|OTTHUMP00000179116|sodium-calcium exchanger form 3|sodium/calcium exchanger SLC8A3|solute carrier family 8 (sodium-calcium exchanger), member 3
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