SLC6A11 monoclonal antibody (M10), clone 2C3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC6A11.
Immunogen
SLC6A11 (NP_055044.1, 164 a.a. ~ 225 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.56 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLC6A11 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — SLC6A11
Entrez GeneID
6538GeneBank Accession#
NM_014229Protein Accession#
NP_055044.1Gene Name
SLC6A11
Gene Alias
GAT-3, GAT3
Gene Description
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
Omim ID
607952Gene Ontology
HyperlinkGene Summary
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11.[supplied by OMIM
Other Designations
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Disease
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