SLC2A4 monoclonal antibody (M05), clone 2C11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC2A4.
Immunogen
SLC2A4 (NP_001033, 467 a.a. ~ 509 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDEND
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (30.47 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLC2A4 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — SLC2A4
Entrez GeneID
6517GeneBank Accession#
NM_001042Protein Accession#
NP_001033Gene Name
SLC2A4
Gene Alias
GLUT4
Gene Description
solute carrier family 2 (facilitated glucose transporter), member 4
Omim ID
138190Gene Ontology
HyperlinkGene Summary
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq
Other Designations
glucose transporter 4|insulin-responsive glucose transporter type 4
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Interactome
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Pathway
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Disease
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