SLC1A3 monoclonal antibody (M07A), clone 3D1
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More Files
- More Functions
Western Blot detection against Immunogen (34.1 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC1A3.
Immunogen
SLC1A3 (NP_004163.2, 162 a.a. ~ 237 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.1 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SLC1A3
Entrez GeneID
6507GeneBank Accession#
NM_004172Protein Accession#
NP_004163.2Gene Name
SLC1A3
Gene Alias
EA6, EAAT1, FLJ25094, GLAST, GLAST1
Gene Description
solute carrier family 1 (glial high affinity glutamate transporter), member 3
Omim ID
600111Gene Ontology
HyperlinkGene Summary
Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system (Kirschner et al., 1994 [PubMed 8001975]).[supplied by OMIM
Other Designations
glutamate transporter variant EAAT1ex9skip
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Interactome
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Disease
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Publication Reference
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Involvement of Crosstalk between Oct4 and Meis1a in Neural Cell Fate Decision.
Yamada T, Urano-Tashiro Y, Tanaka S, Akiyama H, Tashiro F.
PLoS One 2013 Feb; 8(2):e56997.
Application：WB, Mouse, P19 cells.
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Involvement of Crosstalk between Oct4 and Meis1a in Neural Cell Fate Decision.
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