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SLC1A2 rabbit monoclonal antibody

  • Catalog # : H00006506-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SLC1A2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SLC1A2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SLC1A2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 6506
  • Gene Name:
  • SLC1A2
  • Gene Alias:
  • EAAT2,GLT-1
  • Gene Description:
  • solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Gene Summary:
  • This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • excitatory amino acid transporter 2,excitotoxic amino acid transporter 2,glial high affinity glutamate transporter,glutamate/aspartate transporter II,sodium-dependent glutamate/aspartate transporter 2,solute carrier family 1, member 2
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