SIPA1 monoclonal antibody (M01A), clone 2B4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SIPA1.
Immunogen
SIPA1 (AAH10492, 933 a.a. ~ 1042 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SEIASTCNTILESLSREGQPIPESGDPKGTPKSDAEPEPGNLSEKVSHLESMLRKLQEDLQKEKADRAALEEEVRSLRHNNRRLQAESESAATRLLLASKQLGSPTADLA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (90)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — SIPA1
Entrez GeneID
6494GeneBank Accession#
BC010492Protein Accession#
AAH10492Gene Name
SIPA1
Gene Alias
MGC102688, MGC17037, SPA1
Gene Description
signal-induced proliferation-associated 1
Omim ID
602180Gene Ontology
HyperlinkGene Summary
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq
Other Designations
GTPase-activating protein Spa-1|p130 SPA-1|signal-induced proliferation-associated gene 1|signal-induced proliferation-associated protein 1
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Interactome
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Pathway
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Disease
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