ST3GAL1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ST3GAL1 protein.
Immunogen
ST3GAL1 (NP_003024.1, 1 a.a. ~ 340 a.a) full-length human protein.
Sequence
MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCTCTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ST3GAL1 expression in transfected 293T cell line (H00006482-T01) by ST3GAL1 MaxPab polyclonal antibody.
Lane 1: ST3GAL1 transfected lysate(37.4 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ST3GAL1
Entrez GeneID
6482GeneBank Accession#
NM_003033.2Protein Accession#
NP_003024.1Gene Name
ST3GAL1
Gene Alias
DKFZp666E036, DKFZp779K2051, FLJ36548, Gal-NAc6S, MGC9183, SIAT4A, SIATFL, ST3GalA, ST3GalA.1, ST3GalIA, ST3GalIA,1, ST3O
Gene Description
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Omim ID
607187Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq
Other Designations
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase|Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase|alpha 2,3-ST|sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase)|sialyltransferase 4A (beta-galactoside alpha-2,3-sialy
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Interactome
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Pathway
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Disease
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Publication Reference
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The role of Rab6a and phosphorylation of non-muscle myosin IIA tailpiece in alcohol-induced Golgi disorganization.
Petrosyan A, Casey CA, Cheng PW.
Scientific Reports 2016 Aug; 6:31962.
Application:IF, IP, WB-Ce, Human, VA-13 cells.
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Keratin 1 plays a critical role in Golgi localization of Core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail.
Petrosyan A, Ali MF, Cheng PW.
The Journal of Biological Chemistry 2015 Mar; 290(10):6256.
Application:IF, WB-Tr, Human, Panc1-bC2GnT-M-c-Myc cells, HeLa cells.
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Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases.
Petrosyan A, Cheng PW.
Cell Stress & Chaperones 2014 Mar; 19(2):241.
Application:Pull-Down, WB-Tr, Human, LNCaP cells.
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The role of Rab6a and phosphorylation of non-muscle myosin IIA tailpiece in alcohol-induced Golgi disorganization.
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