ST6GAL1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ST6GAL1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ST6GAL1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ST6GAL1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ST6GAL1
Entrez GeneID
6480GeneBank Accession#
ST6GAL1Gene Name
ST6GAL1
Gene Alias
CD75, MGC48859, SIAT1, ST6GalI, ST6N
Gene Description
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
Omim ID
109675Gene Ontology
HyperlinkGene Summary
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq
Other Designations
CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase|ST6Gal I|alpha 2,6-ST|sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)|sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase)
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Disease
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