SIAH2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SIAH2 partial ORF ( AAH13082, 225 a.a. - 324 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SIAH2
Entrez GeneID
6478GeneBank Accession#
BC013082Protein Accession#
AAH13082Gene Name
SIAH2
Gene Alias
hSiah2
Gene Description
seven in absentia homolog 2 (Drosophila)
Omim ID
602213Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq
Other Designations
seven in absentia homolog 2
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Interactome
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Disease
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