SHMT1 MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
SHMT1 MaxPab polyclonal antibody. Western Blot analysis of SHMT1 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of SHMT1 expression in transfected 293T cell line (H00006470-T01) by SHMT1 MaxPab polyclonal antibody.
Lane 1: SHMT1 transfected lysate(53.13 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SHMT1 protein.
Immunogen
SHMT1 (NP_004160.3, 1 a.a. ~ 483 a.a) full-length human protein.
Sequence
MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SHMT1 MaxPab polyclonal antibody. Western Blot analysis of SHMT1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of SHMT1 expression in transfected 293T cell line (H00006470-T01) by SHMT1 MaxPab polyclonal antibody.
Lane 1: SHMT1 transfected lysate(53.13 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SHMT1
Entrez GeneID
6470GeneBank Accession#
NM_004169.3Protein Accession#
NP_004160.3Gene Name
SHMT1
Gene Alias
CSHMT, MGC15229, MGC24556, SHMT
Gene Description
serine hydroxymethyltransferase 1 (soluble)
Omim ID
182144Gene Ontology
HyperlinkGene Summary
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
14 kDa protein|cytoplasmic serine hydroxymethyltransferase
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Interactome
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Pathway
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Disease
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