SHMT1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant SHMT1.
Immunogen
SHMT1 (NP_004160, 374 a.a. ~ 482 a.a) partial recombinant protein with GST tag.
Sequence
EKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPD
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.1 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SHMT1 polyclonal antibody (A01), Lot # 051213JC01 Western Blot analysis of SHMT1 expression in HepG2 ( Cat # L019V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — SHMT1
Entrez GeneID
6470GeneBank Accession#
NM_004169Protein Accession#
NP_004160Gene Name
SHMT1
Gene Alias
CSHMT, MGC15229, MGC24556, SHMT
Gene Description
serine hydroxymethyltransferase 1 (soluble)
Omim ID
182144Gene Ontology
HyperlinkGene Summary
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
14 kDa protein|cytoplasmic serine hydroxymethyltransferase
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Interactome
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Disease
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