SGCB monoclonal antibody (M02), clone 1C10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SGCB.
Immunogen
SGCB (NP_000223, 87 a.a. ~ 196 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WAVIRIGPNGCDSMEFHESGLLRFKQVSDMGVIHPLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVENNKTSITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (97)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SGCB monoclonal antibody (M02), clone 1C10 Western Blot analysis of SGCB expression in MCF-7 ( Cat # L046V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SGCB on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SGCB is 0.1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SGCB on MCF-7 cell . [antibody concentration 10 ug/ml] -
Gene Info — SGCB
Entrez GeneID
6443GeneBank Accession#
NM_000232Protein Accession#
NP_000223Gene Name
SGCB
Gene Alias
A3b, LGMD2E, SGC
Gene Description
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy
Other Designations
OTTHUMP00000158880|beta-sarcoglycan(43kD dystrophin-associated glycoprotein)|limb girdle muscular dystrophy 2E (non-linked families)|sarcoglycan, beta|sarcoglycan, beta (43kD dystrophin-associated glycoprotein)
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Interactome
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Pathway
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