SFTPC monoclonal antibody (M01), clone 4A10
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SFTPC is 0.3 ng/ml as a capture antibody.
Western Blot detection against Immunogen (47.41 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SFTPC.
Immunogen
SFTPC (AAH05913, 1 a.a. ~ 197 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDVGSKEVLMESPPDYSAAPRGRFGIPRCPVHLKRLLIVVVVVVLIVVVIVGALLMGLHMSQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALNRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAFLGMAVNTLCGEVPLYYI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (77)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (47.41 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SFTPC is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — SFTPC
Entrez GeneID
6440GeneBank Accession#
BC005913Protein Accession#
AAH05913Gene Name
SFTPC
Gene Alias
PSP-C, SFTP2, SMDP2, SP-C
Gene Description
surfactant protein C
Gene Ontology
HyperlinkGene Summary
The SFTPC gene encodes pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. It is produced exclusively by type II alveolar epithelial cells in the lung. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark and Clark, 2005 [PubMed 15927881]). See also SFTPA1 (MIM 178630), SFTPB (MIM 178640), and SFTPD (MIM 178635).[supplied by OMIM
Other Designations
pulmonary surfactant apoprotein-2 SP-C|surfactant, pulmonary-associated protein C
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Interactome
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Disease
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Publication Reference
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Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium.
Wong AP, Keating A, Lu WY, Duchesneau P, Wang X, Sacher A, Hu J, Waddell TK.
The Journal of Clinical Investigation 2009 Feb; 119(2):336.
Application：IF, Mouse, Mouse airway epithelium cells.
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Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium.
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