SELP 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SELP full-length
Host
Human
Theoretical MW (kDa)
90.8
Interspecies Antigen Sequence
Mouse (69)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SELP antibody (H00006403-B01) by Western Blots.
SDS-PAGE Gel
SELP transfected lysate.
Western Blot
Lane 1: SELP transfected lysate ( 90.8 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SELP
Entrez GeneID
6403GeneBank Accession#
BC068533Protein Accession#
AAH68533Gene Name
SELP
Gene Alias
CD62, CD62P, FLJ45155, GMP140, GRMP, LECAM3, PADGEM, PSEL
Gene Description
selectin P (granule membrane protein 140kDa, antigen CD62)
Gene Ontology
HyperlinkGene Summary
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq
Other Designations
OTTHUMP00000032609|antigen CD62|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet alpha-granule membrane protein|selectin P|selectin P (granule membrane protein 140kD, antigen CD62)
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Interactome
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Pathway
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Disease
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