SELP rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SELP peptide using ARM Technology.
Immunogen
A synthetic peptide of human SELP is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SELP peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SELP
Entrez GeneID
6403GeneBank Accession#
SELPGene Name
SELP
Gene Alias
CD62, CD62P, FLJ45155, GMP140, GRMP, LECAM3, PADGEM, PSEL
Gene Description
selectin P (granule membrane protein 140kDa, antigen CD62)
Gene Ontology
HyperlinkGene Summary
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq
Other Designations
OTTHUMP00000032609|antigen CD62|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet alpha-granule membrane protein|selectin P|selectin P (granule membrane protein 140kD, antigen CD62)
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Interactome
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Disease
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