SDHD (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SDHD full-length ORF ( NP_002993.1, 1 a.a. - 159 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAVLWRLSAVCGALGGRALLLRTPVVRPAHISAFLQDRPIPEWCGVQHIHLSPSHHSGSKAASLHWTSERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGLGQVVTDYVHGDALQKAAKAGLLALSALTFAGLCYFNYHDVGICKAVAMLWKL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
43.4
Interspecies Antigen Sequence
Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SDHD
Entrez GeneID
6392GeneBank Accession#
NM_003002.1Protein Accession#
NP_002993.1Gene Name
SDHD
Gene Alias
CBT1, PGL, PGL1, SDH4
Gene Description
succinate dehydrogenase complex, subunit D, integral membrane protein
Gene Ontology
HyperlinkGene Summary
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma. [provided by RefSeq
Other Designations
succinate dehydrogenase complex, subunit D|succinate dehydrogenase ubiquinone cytochrome B small subunit
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Metabolic pathways
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