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SDHC rabbit monoclonal antibody

  • Catalog # : H00006391-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SDHC peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SDHC is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SDHC peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6391
  • GeneBank Accession#:
  • SDHC
  • Gene Name:
  • SDHC
  • Gene Alias:
  • CYB560,CYBL,PGL3,QPS1,SDH3
  • Gene Description:
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
  • Gene Summary:
  • This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032375,cytochrome B large subunit of complex II,integral membrane protein CII-3,integral membrane protein CII-3b,succinate dehydrogenase complex, subunit C,succinate dehydrogenase cytochrome b560 subunit,succinate-ubiquinone oxidoreducatase cy
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