Products

Western Blot (Transfected lysate)

Immunoprecipitation

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

CCL23

Gene Alias

CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23

Gene Description

chemokine (C-C motif) ligand 23

Omim ID

Gene Ontology

Gene Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified. [provided by RefSeq

Other Designations

C6 beta-chemokine|OTTHUMP00000163948|hmrp-2a|macrophage inflammatory protein 3|myeloid progenitor inhibitory factor 1|small inducible cytokine A23|small inducible cytokine subfamily A (Cys-Cys), member 23