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CCL21 rabbit monoclonal antibody

  • Catalog # : H00006366-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CCL21 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CCL21 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CCL21 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6366
  • GeneBank Accession#:
  • CCL21
  • Gene Name:
  • CCL21
  • Gene Alias:
  • 6Ckine,CKb9,ECL,MGC34555,SCYA21,SLC,TCA4
  • Gene Description:
  • chemokine (C-C motif) ligand 21
  • Gene Summary:
  • This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq
  • Other Designations:
  • Efficient Chemoattractant for Lymphocytes,OTTHUMP00000000526,OTTHUMP00000000527,OTTHUMP00000021304,beta chemokine exodus-2,exodus-2,secondary lymphoid tissue chemokine,small inducible cytokine A21,small inducible cytokine subfamily A (Cys-Cys), member 21
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