CCL17 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CCL17 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CCL17 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CCL17 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CCL17
Entrez GeneID
6361GeneBank Accession#
CCL17Gene Name
CCL17
Gene Alias
A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC
Gene Description
chemokine (C-C motif) ligand 17
Omim ID
601520Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq
Other Designations
OTTHUMP00000164673|T cell-directed CC chemokine|small inducible cytokine A17|small inducible cytokine subfamily A (Cys-Cys), member 17|thymus and activation-regulated chemokine
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