CCL11 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CCL11 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CCL11
Entrez GeneID
6356GeneBank Accession#
NM_002986.2Protein Accession#
NP_002977.1Gene Name
CCL11
Gene Alias
MGC22554, SCYA11
Gene Description
chemokine (C-C motif) ligand 11
Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq
Other Designations
eosinophil chemotactic protein|eotaxin|small inducible cytokine A11|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
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Interactome
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Pathway
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Disease
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