CCL8 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CCL8 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CCL8
Entrez GeneID
6355GeneBank Accession#
NM_005623.2Protein Accession#
NP_005614.2Gene Name
CCL8
Gene Alias
HC14, MCP-2, MCP2, SCYA10, SCYA8
Gene Description
chemokine (C-C motif) ligand 8
Omim ID
602283Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq
Other Designations
monocyte chemoattractant protein 2|monocyte chemotactic protein 2|small inducible cytokine A8|small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
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Interactome
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Pathway
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Disease
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