CCL7 monoclonal antibody (M03), clone 4B5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CCL7.
Immunogen
CCL7 (NP_006264, 24 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.1 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CCL7 expression in transfected 293T cell line by CCL7 monoclonal antibody (M03), clone 4B5.
Lane 1: CCL7 transfected lysate(11.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CCL7 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — CCL7
Entrez GeneID
6354GeneBank Accession#
NM_006273Protein Accession#
NP_006264Gene Name
CCL7
Gene Alias
FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7
Gene Description
chemokine (C-C motif) ligand 7
Omim ID
158106Gene Ontology
HyperlinkGene Summary
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq
Other Designations
monocyte chemoattractant protein 3|monocyte chemotactic protein 3|small inducible cytokine A7 (monocyte chemotactic protein 3)
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Interactome
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Pathway
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Disease
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