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CCL5 Pre-design Chimera RNAi

  • Catalog # : H00006352-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens chemokine (C-C motif) ligand 5 (CCL5), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002985
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6352
  • Gene Name:
  • CCL5
  • Gene Alias:
  • D17S136E,MGC17164,RANTES,SCYA5,SISd,TCP228
  • Gene Description:
  • chemokine (C-C motif) ligand 5
  • Gene Summary:
  • This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq
  • Other Designations:
  • SIS-delta,T-cell specific RANTES protein,T-cell specific protein p288,beta-chemokine RANTES,regulated upon activation, normally T-expressed, and presumably secreted,small inducible cytokine A5,small inducible cytokine A5 (RANTES),small inducible cytokine
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