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CCL5 rabbit monoclonal antibody

  • Catalog # : H00006352-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CCL5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CCL5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CCL5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6352
  • GeneBank Accession#:
  • CCL5
  • Gene Name:
  • CCL5
  • Gene Alias:
  • D17S136E,MGC17164,RANTES,SCYA5,SISd,TCP228
  • Gene Description:
  • chemokine (C-C motif) ligand 5
  • Gene Summary:
  • This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq
  • Other Designations:
  • SIS-delta,T-cell specific RANTES protein,T-cell specific protein p288,beta-chemokine RANTES,regulated upon activation, normally T-expressed, and presumably secreted,small inducible cytokine A5,small inducible cytokine A5 (RANTES),small inducible cytokine
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