CCL3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CCL3 full-length ORF ( NP_002974.1, 1 a.a. - 92 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.5
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CCL3
Entrez GeneID
6348GeneBank Accession#
NM_002983.1Protein Accession#
NP_002974.1Gene Name
CCL3
Gene Alias
G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3
Gene Description
chemokine (C-C motif) ligand 3
Gene Ontology
HyperlinkGene Summary
Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988 [PubMed 3279154]). Sherry et al. (1988) [PubMed 3058856] demonstrated 2 protein components of MIP1, called by them alpha and beta.[supplied by OMIM
Other Designations
LD78 alpha beta|small inducible cytokine A3 (homologous to mouse Mip-1a)
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Interactome
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Pathway
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Disease
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Publication Reference
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NK cell intrinsic regulation of MIP-1α by granzyme M.
Baschuk N, Wang N, Watt SV, Halse H, House C, Bird PI, Strugnell R, Trapani JA, Smyth MJ, Andrews DM.
Cell Death & Disease 2014 Mar; 5:e1115.
Application:WB-Ce, Mouse, Nk cells.
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NK cell intrinsic regulation of MIP-1α by granzyme M.
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