CCL1 monoclonal antibody (M02), clone 4E4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CCL1.
Immunogen
CCL1 (NP_002972, 24 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (38); Rat (41)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CCL1 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — CCL1
Entrez GeneID
6346GeneBank Accession#
NM_002981Protein Accession#
NP_002972Gene Name
CCL1
Gene Alias
I-309, P500, SCYA1, SISe, TCA3
Gene Description
chemokine (C-C motif) ligand 1
Omim ID
182281Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq
Other Designations
T lymphocyte-secreted protein I-309|inflammatory cytokine I-309|small inducible cytokine A1|small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
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Interactome
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Pathway
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Disease
- Adenocarcinoma
- Arthritis
- Asthma
- Atherosclerosis
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Bronchiolitis
- Colon cancer
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