CCL1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CCL1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CCL1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CCL1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CCL1
Entrez GeneID
6346GeneBank Accession#
CCL1Gene Name
CCL1
Gene Alias
I-309, P500, SCYA1, SISe, TCA3
Gene Description
chemokine (C-C motif) ligand 1
Omim ID
182281Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq
Other Designations
T lymphocyte-secreted protein I-309|inflammatory cytokine I-309|small inducible cytokine A1|small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
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Interactome
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Pathway
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Disease
- Adenocarcinoma
- Arthritis
- Asthma
- Atherosclerosis
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Bronchiolitis
- Colon cancer
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