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SCN10A Pre-design Chimera RNAi

  • Catalog # : H00006336-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens sodium channel, voltage-gated, type X, alpha (SCN10A), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006514
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6336
  • Gene Name:
  • SCN10A
  • Gene Alias:
  • Nav1.8,PN3,SNS,hPN3
  • Gene Description:
  • sodium channel, voltage-gated, type X, alpha subunit
  • Gene Summary:
  • Voltage-gated sodium channels are integral membrane glycoproteins that are responsible for the initial rising phase of action in most excitable cells. They are composed of a large alpha subunit that may be associated with one or more smaller beta subunits. Sodium channels can be differentiated by their primary structure, kinetics, and relative sensitivity to the neurotoxin tetrodotoxin (TTX). Sodium channels, particularly those with TTX-resistant currents, have been found to accumulate in the region of peripheral nerve injury and may be important in chronic pain. SCN10A encodes a TTX-resistant channel that is restricted to the peripheral sensory nervous system (Rabert et al., 1998 [PubMed 9839820]).[supplied by OMIM
  • Other Designations:
  • sodium channel, voltage-gated, type X, alpha,sodium channel, voltage-gated, type X, alpha polypeptide
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