SCN1B DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human SCN1B DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SCN1B
Entrez GeneID
6324GeneBank Accession#
NM_001037.1Protein Accession#
NP_001028.1Gene Name
SCN1B
Gene Alias
GEFSP1
Gene Description
sodium channel, voltage-gated, type I, beta
Gene Ontology
HyperlinkGene Summary
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.[supplied by OMIM
Other Designations
sodium channel beta-1 subunit|sodium channel, voltage-gated, type I, beta polypeptide
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Disease
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