SCN1B (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SCN1B full-length ORF ( NP_001028.1, 1 a.a. - 218 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.61
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SCN1B
Entrez GeneID
6324GeneBank Accession#
NM_001037.1Protein Accession#
NP_001028.1Gene Name
SCN1B
Gene Alias
GEFSP1
Gene Description
sodium channel, voltage-gated, type I, beta
Gene Ontology
HyperlinkGene Summary
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.[supplied by OMIM
Other Designations
sodium channel beta-1 subunit|sodium channel, voltage-gated, type I, beta polypeptide
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Interactome
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Disease
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