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SCD Pre-design Chimera RNAi

  • Catalog # : H00006319-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens stearoyl-CoA desaturase (delta-9-desaturase) (SCD), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005063
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6319
  • Gene Name:
  • SCD
  • Gene Alias:
  • FADS5,MSTP008,SCD1
  • Gene Description:
  • stearoyl-CoA desaturase (delta-9-desaturase)
  • Gene Summary:
  • Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681]; Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000020279,acyl-CoA desaturase,delta-9-desaturase,fatty acid desaturase,predicted protein of HQ0998,stearoyl-CoA desaturase
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