SC5DL (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SC5DL full-length ORF ( NP_001020127.1, 1 a.a. - 299 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDLVLRVADYYFFTPYVYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDHALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKNPSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
61.7
Interspecies Antigen Sequence
Mouse (84); Rat (82)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SC5DL
Entrez GeneID
6309GeneBank Accession#
NM_001024956.1Protein Accession#
NP_001020127.1Gene Name
SC5DL
Gene Alias
ERG3, S5DES, SC5D
Gene Description
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
3beta-hydroxysteroid-delta5-desaturase|delta-5-desaturase|fungal ERG3, delta-5-desaturase-like|lathosterol 5-desaturase|lathosterol dehydrogenase|lathosterol oxidase|sterol C5-desaturase-like|sterol-C5-desaturase
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Interactome
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Pathway
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Disease
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