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Last updated: 2016/12/4

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SAG Pre-design Chimera RNAi

  • Catalog # : H00006295-R01
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  • Specification
  • Product Description:
  • Homo sapiens S-antigen; retina and pineal gland (arrestin) (SAG), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000541
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6295
  • Gene Name:
  • SAG
  • Gene Alias:
  • DKFZp686D1084,DKFZp686I1383,S-AG
  • Gene Description:
  • S-antigen; retina and pineal gland (arrestin)
  • Gene Summary:
  • Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq
  • Other Designations:
  • S-arrestin,arrestin 1,retinal S-antigen (48 KDa protein),rod photoreceptor arrestin
  • Related Disease
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