RXRG monoclonal antibody (M01), clone 6H1
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RXRG.
Immunogen
RXRG (NP_008848, 1 a.a. ~ 75 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITS
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.99 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RXRG expression in transfected 293T cell line by RXRG monoclonal antibody (M01), clone 6H1.
Lane 1: RXRG transfected lysate(50.871 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RXRG is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — RXRG
Entrez GeneID
6258GeneBank Accession#
NM_006917Protein Accession#
NP_008848Gene Name
RXRG
Gene Alias
NR2B3, RXRC
Gene Description
retinoid X receptor, gamma
Omim ID
180247Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000060418|retinoic acid receptor RXR-gamma|retinoid X receptor-gamma
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Interactome
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Pathway
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Disease
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