RS1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-RS1 full-length
Host
Human
Theoretical MW (kDa)
24.64
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-RS1 antibody (H00006247-B01) by Western Blots.
SDS-PAGE Gel
RS1 transfected lysate.
Western Blot
Lane 1: RS1 transfected lysate ( 24.64 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — RS1
Entrez GeneID
6247GeneBank Accession#
BC141638Protein Accession#
AAI41639.1Gene Name
RS1
Gene Alias
RS, XLRS1
Gene Description
retinoschisin 1
Omim ID
312700Gene Ontology
HyperlinkGene Summary
This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq
Other Designations
OTTHUMP00000023004|X-linked juvenile retinoschisis protein|retinoschisis (X-linked, juvenile) 1
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Disease
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