RPS19 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RPS19 protein.
Immunogen
RPS19 (NP_001013.1, 1 a.a. ~ 145 a.a) full-length human protein.
Sequence
MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RPS19 expression in transfected 293T cell line (H00006223-T02) by RPS19 MaxPab polyclonal antibody.
Lane 1: RPS19 transfected lysate(16.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RPS19
Entrez GeneID
6223GeneBank Accession#
NM_001022.3Protein Accession#
NP_001013.1Gene Name
RPS19
Gene Alias
DBA
Gene Description
ribosomal protein S19
Gene Ontology
HyperlinkGene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq
Other Designations
40S ribosomal protein S19|Diamond-Blackfan anemia
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Interactome
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Disease
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