RPS14 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (42.72 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant RPS14.
Immunogen
RPS14 (AAH06784.1, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag.
Sequence
MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCRELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRTEDVTPIPSDSTRRKGGRRGRRL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (42.72 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — RPS14
Entrez GeneID
6208GeneBank Accession#
BC006784Protein Accession#
AAH06784.1Gene Name
RPS14
Gene Alias
EMTB
Gene Description
ribosomal protein S14
Omim ID
130620Gene Ontology
HyperlinkGene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
40S ribosomal protein S14|emetine resistance
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Interactome
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Disease
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Publication Reference
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Dexamethasone and lenalidomide have distinct functional effects on.
Narla A, Dutt S, McAuley JR, Al-Shahrour F, Hurst S, McConkey M, Neuberg D, Ebert BL.
Blood 2011 Aug; 118(8):2296.
Application：WB-Ce, Human, Human erythroid cells.
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Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.
Dutt S, Narla A, Lin K, Mullally A, Abayasekara N, Megerdichian C, Wilson FH, Currie T, Khanna-Gupta A, Berliner N, Kutok JL, Ebert BL.
Blood 2011 Mar; 117(9):2567.
Application：WB, Human, A549 cells.
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Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.
Ebert BL, Pretz J, Bosco J, Chang CY, Tamayo P, Galili N, Raza A, Root DE, Attar E, Ellis SR, Golub TR.
Nature 2008 Jan; 451(7176):335.
Application：WB, Human, Normal CD34+ human haematopoietic progenitor cells.
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Dexamethasone and lenalidomide have distinct functional effects on.
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