MRPL12 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MRPL12 protein.
Immunogen
MRPL12 (NP_002940.2, 1 a.a. ~ 198 a.a) full-length human protein.
Sequence
MLPAAARPLWGPCLGLRAAAFRLARRQVPCVCAVRHMRSSGHQRCEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLVPMGGVMSGAVPAAAAQEAVEEDIPIAKERTHFTVRLTEAKPVDKVKLIKEIKNYIQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MRPL12 MaxPab rabbit polyclonal antibody. Western Blot analysis of MRPL12 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of MRPL12 expression in transfected 293T cell line (H00006182-T02) by MRPL12 MaxPab polyclonal antibody.
Lane 1: MRPL12 transfected lysate(21.30 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MRPL12 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — MRPL12
Entrez GeneID
6182GeneBank Accession#
NM_002949Protein Accession#
NP_002940.2Gene Name
MRPL12
Gene Alias
5c5-2, FLJ60124, L12mt, MGC8610, MRP-L31/34, MRPL7, MRPL7/L12, RPML12
Gene Description
mitochondrial ribosomal protein L12
Omim ID
602375Gene Ontology
HyperlinkGene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq
Other Designations
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