RORC monoclonal antibody (M01), clone 1G7
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More Files
- More Functions
Western Blot (Tissue lysate)
RORC monoclonal antibody (M01), clone 1G7. Western Blot analysis of RORC expression in human kidney.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RORC is 1 ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.4 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RORC.
Immunogen
RORC (NP_005051.2, 412 a.a. ~ 517 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.4 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
RORC monoclonal antibody (M01), clone 1G7. Western Blot analysis of RORC expression in human kidney.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RORC is 1 ng/ml as a capture antibody.ELISA
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Gene Info — RORC
Entrez GeneID
6097GeneBank Accession#
NM_005060Protein Accession#
NP_005051.2Gene Name
RORC
Gene Alias
MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Gene Description
RAR-related orphan receptor C
Omim ID
602943Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000015253|RAR-related orphan receptor C, isoform a|RAR-related orphan receptor gamma|nuclear receptor ROR-gamma|retinoic acid-binding receptor gamma|retinoid-related orphan receptor gamma
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Interactome
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Disease
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