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RORC rabbit monoclonal antibody

  • Catalog # : H00006097-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RORC peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RORC is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RORC peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6097
  • GeneBank Accession#:
  • RORC
  • Gene Name:
  • RORC
  • Gene Alias:
  • MGC129539,NR1F3,RORG,RZR-GAMMA,RZRG,TOR
  • Gene Description:
  • RAR-related orphan receptor C
  • Gene Summary:
  • The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000015253,RAR-related orphan receptor C, isoform a,RAR-related orphan receptor gamma,nuclear receptor ROR-gamma,retinoic acid-binding receptor gamma,retinoid-related orphan receptor gamma
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