RORB monoclonal antibody (M01), clone 4B4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RORB.
Immunogen
RORB (NP_008845, 136 a.a. ~ 224 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHL
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.53 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RORB expression in transfected 293T cell line by RORB monoclonal antibody (M01), clone 4B4.
Lane 1: RORB transfected lysate (Predicted MW: 52.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RORB is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — RORB
Entrez GeneID
6096GeneBank Accession#
NM_006914Protein Accession#
NP_008845Gene Name
RORB
Gene Alias
NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1
Gene Description
RAR-related orphan receptor B
Omim ID
601972Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. [provided by RefSeq
Other Designations
OTTHUMP00000021486|RAR-related orphan receptor beta|nuclear receptor RZR-beta|retinoic acid-binding receptor beta|retinoid-related orphan receptor beta
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Interactome
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Disease
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